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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: XRCC1 All Species: 7.27
Human Site: T284 Identified Species: 16
UniProt: P18887 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P18887 NP_006288 633 69526 T284 A P T R T P A T A P V P A R A
Chimpanzee Pan troglodytes XP_512717 596 65689 E268 K P R G E G T E P R R P R A G
Rhesus Macaque Macaca mulatta XP_001100256 645 69984 S326 A S S A S P V S R A I G S T S
Dog Lupus familis XP_533653 654 71801 T307 A P T R T P A T P V P A P A R
Cat Felis silvestris
Mouse Mus musculus Q60596 631 68952 P286 S R T P A A A P A S T P A Q R
Rat Rattus norvegicus Q9ESZ0 631 68817 P286 S R T P A A T P A S T P A Q K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516926 549 59237 G245 F A C S D A G G C G G P S G K
Chicken Gallus gallus
Frog Xenopus laevis NP_001080711 651 73244 P293 V E T H T V A P T K K P S P S
Zebra Danio Brachydanio rerio NP_001003988 615 68071 S283 S M G T S P S S R A S P A Q K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572217 614 68751 N283 D V K D A E V N A K K Q R L S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001180271 512 56847 E207 S V P N K S K E S K P Q P A T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.8 82.3 86 N.A. 86 86.5 N.A. 47.7 N.A. 53.9 51.1 N.A. 20.7 N.A. N.A. 38.8
Protein Similarity: 100 94.1 83 88.3 N.A. 91.1 91 N.A. 56.5 N.A. 67.7 68.8 N.A. 36.9 N.A. N.A. 55.1
P-Site Identity: 100 13.3 13.3 53.3 N.A. 33.3 26.6 N.A. 6.6 N.A. 26.6 20 N.A. 6.6 N.A. N.A. 0
P-Site Similarity: 100 13.3 53.3 53.3 N.A. 46.6 40 N.A. 13.3 N.A. 40 53.3 N.A. 13.3 N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 28 10 0 10 28 28 37 0 37 19 0 10 37 28 10 % A
% Cys: 0 0 10 0 0 0 0 0 10 0 0 0 0 0 0 % C
% Asp: 10 0 0 10 10 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 10 0 0 10 10 0 19 0 0 0 0 0 0 0 % E
% Phe: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 10 10 0 10 10 10 0 10 10 10 0 10 10 % G
% His: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % I
% Lys: 10 0 10 0 10 0 10 0 0 28 19 0 0 0 28 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % L
% Met: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 10 0 0 0 10 0 0 0 0 0 0 0 % N
% Pro: 0 28 10 19 0 37 0 28 19 10 19 64 19 10 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 19 0 28 0 % Q
% Arg: 0 19 10 19 0 0 0 0 19 10 10 0 19 10 19 % R
% Ser: 37 10 10 10 19 10 10 19 10 19 10 0 28 0 28 % S
% Thr: 0 0 46 10 28 0 19 19 10 0 19 0 0 10 10 % T
% Val: 10 19 0 0 0 10 19 0 0 10 10 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _